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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SETD1B
All Species:
12.42
Human Site:
T1586
Identified Species:
21.03
UniProt:
Q9UPS6
Number Species:
13
Phosphosite Substitution
Charge Score:
0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UPS6
NP_055863.1
1923
208732
T1586
P
R
G
R
D
E
V
T
E
E
Y
M
E
L
A
Chimpanzee
Pan troglodytes
XP_523492
1707
185692
S1381
E
E
S
S
D
S
S
S
S
S
D
G
E
G
A
Rhesus Macaque
Macaca mulatta
XP_001092031
624
66545
R312
P
A
V
T
F
K
A
R
R
H
E
S
K
F
T
Dog
Lupus familis
XP_543382
1925
209302
T1589
P
R
G
R
D
D
V
T
E
E
F
M
D
L
A
Cat
Felis silvestris
Mouse
Mus musculus
Q8CFT2
1985
215333
E1649
P
R
R
D
E
V
T
E
E
Y
V
D
L
A
K
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510235
695
75024
P383
Q
Y
S
H
T
P
P
P
A
P
H
G
H
T
G
Chicken
Gallus gallus
Q5F3P8
2008
223067
E1676
W
N
E
D
F
K
E
E
E
A
H
A
K
P
K
Frog
Xenopus laevis
Q66J90
1938
216239
E1604
W
N
E
V
L
K
E
E
E
E
D
I
S
K
H
Zebra Danio
Brachydanio rerio
Q1LY77
1844
204122
T1509
I
I
P
K
V
E
E
T
S
F
Y
V
E
E
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001015221
1641
188364
C1328
K
N
V
H
F
V
P
C
D
M
Y
K
T
R
D
Honey Bee
Apis mellifera
XP_395451
1406
159180
Y1094
V
E
E
P
I
V
T
Y
K
E
R
D
L
M
S
Nematode Worm
Caenorhab. elegans
Q18221
1507
171664
T1195
P
P
P
R
F
K
K
T
F
K
P
R
S
E
E
Sea Urchin
Strong. purpuratus
XP_791552
1963
220543
S1588
S
A
T
M
D
D
S
S
E
K
T
M
S
G
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q8X0S9
1313
145607
I1001
P
K
D
F
N
L
D
I
G
T
L
K
L
V
P
Conservation
Percent
Protein Identity:
100
37.3
27.9
91.9
N.A.
87.7
N.A.
N.A.
23.1
61.5
55
51
N.A.
24.7
23.9
22.3
21.3
Protein Similarity:
100
50.3
28.8
93.9
N.A.
90.2
N.A.
N.A.
26.7
71.1
66.6
63.6
N.A.
39.4
38.6
35.2
35.2
P-Site Identity:
100
20
6.6
80
N.A.
20
N.A.
N.A.
0
6.6
13.3
26.6
N.A.
6.6
6.6
20
20
P-Site Similarity:
100
26.6
20
100
N.A.
26.6
N.A.
N.A.
6.6
26.6
26.6
40
N.A.
13.3
26.6
33.3
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
22.2
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
35.4
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
15
0
0
0
0
8
0
8
8
0
8
0
8
22
% A
% Cys:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% C
% Asp:
0
0
8
15
29
15
8
0
8
0
15
15
8
0
8
% D
% Glu:
8
15
22
0
8
15
22
22
43
29
8
0
22
15
8
% E
% Phe:
0
0
0
8
29
0
0
0
8
8
8
0
0
8
0
% F
% Gly:
0
0
15
0
0
0
0
0
8
0
0
15
0
15
8
% G
% His:
0
0
0
15
0
0
0
0
0
8
15
0
8
0
8
% H
% Ile:
8
8
0
0
8
0
0
8
0
0
0
8
0
0
0
% I
% Lys:
8
8
0
8
0
29
8
0
8
15
0
15
15
8
15
% K
% Leu:
0
0
0
0
8
8
0
0
0
0
8
0
22
15
0
% L
% Met:
0
0
0
8
0
0
0
0
0
8
0
22
0
8
0
% M
% Asn:
0
22
0
0
8
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
43
8
15
8
0
8
15
8
0
8
8
0
0
8
15
% P
% Gln:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
22
8
22
0
0
0
8
8
0
8
8
0
8
0
% R
% Ser:
8
0
15
8
0
8
15
15
15
8
0
8
22
0
15
% S
% Thr:
0
0
8
8
8
0
15
29
0
8
8
0
8
8
8
% T
% Val:
8
0
15
8
8
22
15
0
0
0
8
8
0
8
0
% V
% Trp:
15
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
0
0
0
8
0
8
22
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _